基因名:
PSENEN
产品别名:
ACNINV2; MDS033; MSTP064; PEN-2; PEN2; PSENEN; presenilin enhancer, gamma-secretase subunit; presenilin enhancer, gamma-secretase subunit; gamma-secretase subunit PEN-2; hematopoietic stem/progenitor cells protein MDS033; presenilin enhancer 2 homolog; 早老素γ分泌酶2;
背景信息:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.