基因名：
CCL28
产品别名：
CCK1； MEC； SCYA28； CCL28； C-C motif chemokine ligand 28； C-C motif chemokine ligand 28； C-C motif chemokine 28； CC chemokine CCL28； chemokine (C-C motif) ligand 28； mucosae-associated epithelial chemokine； small inducible cytokine A28； small inducible cytokine subfamily A (Cys-Cys), member 28； 粘膜关联上皮趋化因子(MEC)；
背景信息：
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.
