基因名：
Clec7a
产品别名：
BGR； Clecsf12； beta-GR； Clec7a； C-type lectin domain family 7, member a； C-type lectin domain family 7, member a； C-type lectin domain family 7 member A； C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12； C-type lectin superfamily member 12； DC-associated C-type lectin 1； beta-glucan receptor； dectin-1； dendritic cell-associated C-type lectin 1； C-型凝集素域家族7成员A(CLEC7A)； β葡聚糖受体；
背景信息：
Dectin-1 was recently identified as the most important receptor for beta-glucan. It is a type II transmembrane protein which binds beta-1,3 and beta-1,6 glucans, and is expressed on most cells of the innate immune system and has been implicated in phagocytosis as well as killing of fungi by macrophages, neutrophils and dendritic cells. Recognition of beta-glucan by dectin-1 triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi, which especially benefits immunocompromised patients against opportunistic fungal infection.
