基因名：
Necab3
产品别名：
2900010M17Rik； AI853434； Apba2bp； Nip1； XB51； Necab3； N-terminal EF-hand calcium binding protein 3； N-terminal EF-hand calcium binding protein 3； N-terminal EF-hand calcium-binding protein 3； X11L-binding protein 51； amyloid beta (A4) precursor protein-binding family A member 1 binding protein； amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein； amyloid beta A4 protein-binding family A member 2-binding protein； mXB51； 神经细胞钙结合蛋白；
背景信息：
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
