基因名:
EMSY
产品别名:
C11orf30; GL002; EMSY; EMSY transcriptional repressor, BRCA2 interacting; EMSY transcriptional repressor, BRCA2 interacting; BRCA2-interacting transcriptional repressor EMSY; EMSY, BRCA2 interacting transcriptional repressor; protein EMSY; EMSY蛋白;
背景信息:
EMSY binds BRCA2 within a region (exon 3) deleted in cancer. EMSY is capable of silencing the activation potential of BRCA2 exon 3, associates with chromatin regulators HP1 and BS69, and localizes to sites of repair following DNA damage. Its levels are amplified in breast and ovarian cancer.