基因名：
SMYD2
产品别名：
HSKM-B； KMT3C； ZMYND14； SMYD2； SET and MYND domain containing 2； SET and MYND domain containing 2； N-lysine methyltransferase SMYD2； SET and MYND domain-containing protein 2； histone methyltransferase SMYD2； lysine N-methyltransferase 3C； zinc finger, MYND domain containing 14； 组蛋白甲基转移酶SMYD2； 组蛋白赖氨酸N-甲基转移酶3C；
背景信息：
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.
