基因名:
RGMA
产品别名:
RGM; RGMA; repulsive guidance molecule BMP co-receptor a; repulsive guidance molecule BMP co-receptor a; repulsive guidance molecule A; RGM domain family, member A; repulsive guidance molecule family member a; 反义导向分子RGMA;
背景信息:
Repulsive guidance molecule A(RGMA) is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1, BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.