基因名:
COQ8A
产品别名:
ADCK3; ARCA2; CABC1; COQ10D4; COQ8; SCAR9; COQ8A; coenzyme Q8A; coenzyme Q8A; atypical kinase COQ8A, mitochondrial; aarF domain-containing protein kinase 3; atypical kinase ADCK3, mitochondrial; chaperone activity of bc1 complex-like, mitochondrial; chaperone, ABC1 activity of bc1 complex homolog; coenzyme Q protein 8A; coenzyme Q8 homolog; 伴侣蛋白bc1同源复合体;
背景信息:
This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008]