基因名:
EPPIN
产品别名:
CT71; CT72; SPINLW1; WAP7; WFDC7; dJ461P17.2; EPPIN; epididymal peptidase inhibitor; epididymal peptidase inhibitor; eppin; WAP four-disulfide core domain protein 7; cancer/testis antigen 71; cancer/testis antigen 72; epididymal protease inhibitor; epididymis secretory sperm binding protein; protease inhibitor WAP7; serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin); 附睾蛋白酶抑制蛋白+O13844;
背景信息:
This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. [provided by RefSeq].