重组PDZ结构域蛋白GOPC

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重组PDZ结构域蛋白GOPC

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant GOPC
Recombinant golgi associated PDZ and coiled-coil motif containing protein

基因名：

GOPC

产品别名：

CAL； FIG； GOPC1； PIST； dJ94G16.2； GOPC； golgi associated PDZ and coiled-coil motif containing； golgi associated PDZ and coiled-coil motif containing； Golgi-associated PDZ and coiled-coil motif-containing protein； CFTR-associated ligand； PDZ protein interacting specifically with TC10； PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10； dJ94G16.2 PIST； fused in glioblastoma； golgi-associated PDZ and coiled-coil motif containing protein； PDZ结构域蛋白GOPC；

背景信息：

PIST (PDZ protein interacting specifically with TC10), also known as GOPC (golgi associated PDZ and coiled-coil motif containing), CAL or FIG, is a 462 amino acid protein that localizes to the cytoplasm, as well as to the membrane of the golgi apparatus and to the cell junction. Expressed ubiquitously and containing one PDZ (DHR) domain, PIST functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation. Additionally, PIST is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy. Chromosomal aberrations in the gene encoding PIST are found in glioblastoma multiform (GBM), a common and aggressive form of brain tumor, suggesting a role for mutated PIST in carcinogenesis. Three isoforms of PIST exist due to alternative splicing events.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。