基因名:
CD248
产品别名:
CD164L1; TEM1; CD248; CD248 molecule; CD248 molecule; endosialin; 2610111G01Rik; CD164 sialomucin-like 1; CD248 antigen, endosialin; CD248 molecule, endosialin; tumor endothelial marker 1; 内涎蛋白/内皮唾液酸蛋白;
背景信息:
The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal fibroblasts, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing. TEM1 is being investigated as a potential target for cancer treatment.