基因名:
CHMP1B
产品别名:
C10orf2; C18-ORF2; C18orf2; CHMP1.5; Vps46-2; Vps46B; hVps46-2; CHMP1B; charged multivesicular body protein 1B; charged multivesicular body protein 1B; charged multivesicular body protein 1b; chromatin modifying protein 1B; chromatin-modifying protein 1b; vacuolar protein sorting 46-2; vacuolar protein sorting-associated protein 46-2; 染色质修饰蛋白1B;
背景信息:
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression