基因名:
WDFY1
产品别名:
FENS-1; FENS1; WDF1; ZFYVE17; WDFY1; WD repeat and FYVE domain containing 1; WD repeat and FYVE domain containing 1; WD repeat and FYVE domain-containing protein 1; FYVE domain-containing protein localized to endosomes 1; WD40- and FYVE domain-containing protein 1; phosphoinositide-binding protein SR1; zinc finger FYVE domain-containing protein 17; 磷酸肌醇结合蛋白1;
背景信息:
WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDFY1 (WD repeat and FYVE domain containing 1), also known as WDF1, FENS-1 or ZFYVE17, is a 410 amino acid protein that localizes to the early endosome and contains one FYVE-type zinc finger and seven WD repeats through which it may play a role in protein trafficking and signal transduction.