基因名：
Pdcd1lg2
产品别名：
B7-DC； Btdc； F730015O22Rik； PD-L2； Pdcd1lg2； programmed cell death 1 ligand 2； programmed cell death 1 ligand 2； programmed cell death 1 ligand 2； PD-1 ligand 2； PDCD1 ligand 2； butyrophilin B7-DC； butyrophilin-like protein； programmed death ligand 2； 程序性死亡配体2蛋白； 程序性死亡配体2（CD273）； 程序性死亡配体2（CD273）蛋白； 细胞程序性死亡蛋白1配体2(PDL2)； 细胞程序性死亡蛋白1配体2(PDL2)真核蛋白；
背景信息：
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
