基因名:
Bcl11b
产品别名:
9130430L19Rik; AI604821; B630002E05Rik; BCL-11B; Ctip2; Rit1; Bcl11b; B cell leukemia/lymphoma 11B; B cell leukemia/lymphoma 11B; B-cell lymphoma/leukemia 11B; B-cell CLL/lymphoma 11B; B-cell lymphoma/leukaemia 11B; COUP-TF-interacting protein 2; mRit1; radiation-induced tumor suppressor gene 1 protein; B淋巴细胞白血病/淋巴瘤11B;
背景信息:
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]