基因名:
SENP2
产品别名:
AXAM2; SMT3IP2; SENP2; SUMO specific peptidase 2; SUMO specific peptidase 2; sentrin-specific protease 2; SMT3-specific isopeptidase 2; SUMO1/sentrin/SMT3 specific peptidase 2; SUMO1/sentrin/SMT3 specific protease 2; sentrin (SUMO1) specific peptidase 2; sentrin/SUMO-specific protease SENP2; 泛素样蛋白特异性蛋白酶2;
背景信息:
SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.