基因名:
CIAO3
产品别名:
HPRN; IOP1; LET1L; NAR1; NARFL; PRN; CIAO3; cytosolic iron-sulfur assembly component 3; cytosolic iron-sulfur assembly component 3; cytosolic iron-sulfur assembly component 3; LET1 like/JFP15; cytosolic Fe-S cluster assembly factor NARFL; iron-only hydrogenase-like protein 1; nuclear prelamin A recognition factor like; protein related to Narf; NARFL蛋白;
背景信息:
NARFL (nuclear prelamin A recognition factor-like), also known as cytosolic Fe-S cluster assembly factor NARFL, HPRN, PRN (protein related to Narf), LET1L or IOP1 (iron-only hydrogenase-like protein 1), is a 476 amino acid protein belonging to the NARF family. Widely expressed, NARFL is required for extramitochondrial sulfur and iron protein maturation and may indirectly negatively regulate HIF-1?expression. Existing as three alternatively spliced isoforms, NARFL is encoded by a gene that maps to human chromosome 16p13.3 and murine chromosome 17 A3.3.