基因名：
MTARC1
产品别名：
MARC1； MOSC1； MTARC1； mitochondrial amidoxime reducing component 1； mitochondrial amidoxime reducing component 1； mitochondrial amidoxime-reducing component 1； MOCO sulphurase C-terminal domain containing 1； MOSC domain-containing protein 1, mitochondrial； moco sulfurase C-terminal domain-containing protein 1； molybdenum cofactor sulfurase C-terminal domain-containing protein 1； MOSC1蛋白； 含MOCO硫化酶羧基端域蛋白1(MOSC1)；
背景信息：
MOSC1 is a 337 amino acid mitochondrial protein that is thought to function as an oxidoreductase. Existing as three alternatively spliced isoforms, MOSC1 contains one MOSC domain and binds molybdenum as a cofactor. The gene encoding MOSC1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
