基因名:
Map1lc3b
产品别名:
LC3B; Map1lc3; Mpl3; zbs559; Map1lc3b; microtubule-associated protein 1 light chain 3 beta; microtubule-associated protein 1 light chain 3 beta; microtubule-associated proteins 1A/1B light chain 3B; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; autophagy-related protein LC3 B; autophagy-related ubiquitin-like modifier LC3 B; microtubule-associated proteins 1A/1B light chain 3; 微管关联蛋白1轻链3β(MAP1LC3b); 磷酸化自噬微管相关蛋白轻链3; 自噬微管相关蛋白轻链3; 自噬微管相关蛋白轻链3A/3B; 自噬微管相关蛋白轻链β3;
背景信息:
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) is a member of the highly conserved ATG8 protein family. ATG8 proteins are present in all known eukaryotic organisms. MAP1LC3B is one of the four genes in the MAP1LC3 subfamily (others include MAP1LC3A, MAP1LC3C, and MAP1LC3B2). It is moat abundantly expressed in heart, brain, skeletal muscle and testis. LMAP1LC3B is a subunit of neuronal microtubule and functions in formation of autophagosomal vacuoles (autophagosomes). It associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. MAP1LC3B also plays a role in autophagy, a process that involves the bulk degradation of cytoplasmic component.