基因名:
Lrrk2
产品别名:
4921513O20Rik; 9330188B09Rik; AW561911; D630001M17Rik; Gm927; cI-46; Lrrk2; leucine-rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; 亮氨酸丰富重复激酶2(LRRK2); 富亮氨酸重复激酶2; 磷酸化富亮氨酸重复激酶2;
背景信息:
LRRK2 (Dardarin) is encoded by the gene LRRK2. Genetic mutations of LRRK2 have been linked to Parkinsonism and synucleinopathies. LRRK2 belongs to the ROCO protein family and includes a protein kinase domain of the MAPKKK class and several other major functional domains.