基因名:
Bcl2l14
产品别名:
4930452K23Rik; 4933405K19Rik; 9030625M01Rik; AI429211; Bcl-G; Bclg; Bcl2l14; BCL2-like 14 (apoptosis facilitator); BCL2-like 14 (apoptosis facilitator); apoptosis facilitator Bcl-2-like protein 14; apoptosis regulator BCL-G; Bcl2样凋亡蛋白14;
背景信息:
Bcl-G is a novel pro-apoptotic member of the Bcl-2 family. The human Bcl-G gene encodes two proteins through alternative mRNA splicing, Bcl-G(L) (long) and Bcl-G(S) (short) consisting of 327 and 252 amino acids in length, respectively. Bcl-G(L) mRNA is expressed widely in adult human tissues, whereas Bcl-G(S) mRNA was found only in testis. Overexpression of Bcl-G(L) or Bcl-G(S) in cells induced apoptosis although Bcl-G(S) was far more potent than Bcl-G(L).