基因名:
Clec14a
产品别名:
1200003C23Rik; AI642649; Clec14a; C-type lectin domain family 14, member a; C-type lectin domain family 14, member a; C-type lectin domain family 14 member A; 表皮生长因子受体5;
背景信息:
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting.