基因名:
Mtdh
产品别名:
2610103J23Rik; 3D3; 3D3/Lyric; AEG-1; AV353288; D8Bwg1112e; Lyric; Mtdh; metadherin; metadherin; protein LYRIC; lysine-rich CEACAM1 co-isolated protein; metastasis adhesion protein; 异粘蛋白(MTDH); 星形胶质细胞升高基因1; 磷酸化星形胶质细胞升高基因1;
背景信息:
LYRIC is a type II membrane protein, the precise role of which has yet to be defined. It is expressed in breast and prostate carcinoma and is a potential mediator of lung metastasis. It has also been found in mouse Purkinje neurons and cerebellum. In epithelial cells it is recruited to tight junctions (TJ) during the maturation of the TJ complexes. LYRIC co-localizes with beta-catenin in normal and tumour tissues.