基因名:
Rpf2
产品别名:
2810470K21Rik; AU040229; AU043242; Bxdc1; Rpf2; ribosome production factor 2 homolog; ribosome production factor 2 homolog; ribosome production factor 2 homolog; brix domain containing 1; brix domain-containing protein 1; ribosome biogenesis protein RPF2 homolog; BXDC1蛋白;
背景信息:
BXDC1 is a 306 amino acid protein encoded by the human gene BXDC1. BXDC1 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region with homology to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes RPF1, RPF2 and SSF1 or SSF2. This complex is required for the biogenesis of the 60S ribosomal subunit.