基因名:
Smc6
产品别名:
2810489L22Rik; 3830418C19Rik; AA990493; AU018782; AW742439; SMC-6; Smc6l1; mKIAA4103; Smc6; structural maintenance of chromosomes 6; structural maintenance of chromosomes 6; structural maintenance of chromosomes protein 6; SMC protein 6; SMC6 structural maintenance of chromosomes 6-like 1; 染色体结构维持蛋白6;
背景信息:
SMC5/6 complex is recruited to nuclease induced double strand breaks (DSBs) and is required for the recruitment of cohesin to DSBs. The human SMC5/6 complex and the SUMO ligase activity of hMMS21 are required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells.