基因名：
Wdr83
产品别名：
1500041N16Rik； Morg1； Wdr83； WD repeat domain containing 83； WD repeat domain containing 83； WD repeat domain-containing protein 83； MAPK cascade scaffold protein； MAPK organizer 1； mitogen-activated protein kinase organizer 1； MORG1蛋白； 丝裂原活化蛋白激酶组织蛋白1；
背景信息：
This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
