基因名:
Ddx59
产品别名:
1210002B07Rik; 4833411G06Rik; Ddx59; DEAD box helicase 59; DEAD box helicase 59; probable ATP-dependent RNA helicase DDX59; DEAD (Asp-Glu-Ala-Asp) box polypeptide 59; DEAD box protein 59; zinc finger HIT domain-containing protein 5; ATP依赖RNA解旋酶DDX59;
背景信息:
DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX59 is a 619 amino acid member of the DEAD box helicase protein family. Like many DEAD box helicase family members, DDX59 contains a Q motif, which controls ATP binding and hydrolysis. Expressed as two isoforms produced by alternative splicing, DDX59 contains one helicase C-terminal domain and one HIT-type zinc finger.