基因名:
Pwwp3a
产品别名:
2610019J09; 9430059D04Rik; Mum1; UBE-1C2; Pwwp3a; PWWP domain containing 3A, DNA repair factor; PWWP domain containing 3A, DNA repair factor; PWWP domain-containing DNA repair factor 3A; MUM-1; PWWP domain-containing protein MUM1; melanoma associated antigen (mutated) 1; mutated melanoma-associated antigen 1; 神经突触前膜胞内蛋白13; 突变的黑色素瘤相关抗原1;
背景信息:
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.