重组磷酸化蛋白磷酸激酶PKC/CPI-17

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重组蛋白磷酸激酶PKC/CPI-17
Recombinant Ppp1r14a

基因名：

Ppp1r14a

产品别名：

1110001M11Rik； CPI-17； Cpi17； Ppp1r14a； protein phosphatase 1, regulatory inhibitor subunit 14A； protein phosphatase 1, regulatory inhibitor subunit 14A； protein phosphatase 1 regulatory subunit 14A； 17 kDa PKC-potentiated inhibitory protein of PP1； protein kinase C-potentiated inhibitor protein of 17 kDa；磷酸化蛋白磷酸激酶PKC/CPI-17；蛋白磷酸激酶PKC/CPI-17；

背景信息：

Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase. PPP1R14A is the inhibitor of PPP1CA. When phosphorylated, PPP1R14A has over 1000-fold higher inhibitory activity, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. In addition, inhibition of PPP1R14A also enhances contraction of smooth muscle in the absence of increment of intracellular Ca2+ concentration.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。