基因名:
Draxin
产品别名:
2610109H07Rik; neucrin; Draxin; dorsal inhibitory axon guidance protein; dorsal inhibitory axon guidance protein; draxin; dorsal repulsive axon guidance protein; 1号染色体开放阅读框187;
背景信息:
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.