基因名：
Aifm2
产品别名：
5430437E11Rik； Amid； D730001I10Rik； FSP1； PRG3； Aifm2； apoptosis-inducing factor, mitochondrion-associated 2； apoptosis-inducing factor, mitochondrion-associated 2； ferroptosis suppressor protein 1； apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death； apoptosis-inducing factor 2； apoptosis-inducing factor homologous mitochondrion-associated inducer of death； apoptosis-inducing factor-like mitchondrion-associated inducer of death； apoptosis-inducing factor-like mitochondrion-associated inducer of death； p53-responsive gene 3 protein； 线粒体凋亡诱导因子2；
背景信息：
Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest. Tissue specificity: Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively. Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung, kidney, and pancreas. Both transcripts expressed following p53/TP53 induction. The shorter 1.8 kb transcript seems to be the major transcript in EB1 colon cancer cells.
