基因名:
Epgn
产品别名:
2310069M11Rik; epigen; Epgn; epithelial mitogen; epithelial mitogen; epigen; EPG; Epigen蛋白(EPG); 上皮细胞有丝分裂蛋白;
背景信息:
Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.