基因名：
Rspo3
产品别名：
2810459H04Rik； AW742308； Cristin1； Thsd2； Rspo3； R-spondin 3； R-spondin 3； R-spondin-3； R-spondin 3 homolog； cabriolet； cristin 1； cysteine-rich and single thrombospondin domain-containing protein 1； nucleopondin； roof plate-specific spondin-3； thrombospondin, type I, domain 2； R-脊椎蛋白3(RSPO3)；
背景信息：
This protein belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development.
