基因名：
Steap2
产品别名：
4921538B17Rik； AI930049； AW045895； IPCA-1； IPCA1； PCANAP1； STAMP1； STMP； Steap2； six transmembrane epithelial antigen of prostate 2； six transmembrane epithelial antigen of prostate 2； metalloreductase STEAP2； 前列腺六跨膜表皮抗原2(STEAP2)； 前列腺跨膜上皮2抗原；
背景信息：
This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
