基因名:
Nuak2
产品别名:
1200013B22Rik; Omphk2; Snark; mKIAA0537; Nuak2; NUAK family, SNF1-like kinase, 2; NUAK family, SNF1-like kinase, 2; NUAK family SNF1-like kinase 2; SNF1/AMP-activated protein kinase; omphalocele kinase 2; SNF1/AMP激酶相关激酶2;
背景信息:
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.