基因名：
Hopx
产品别名：
1110018K11Rik； 1200015P04Rik； 2300002F06Rik； AI848177； AW490897； Cameo； Hdop； Hod； Hop； Ob1； Obl； Toto； Hopx； HOP homeobox； HOP homeobox； homeodomain-only protein； homeobox only domain； homeobox-only protein； mOB1； odd homeobox 1； odd homeobox protein 1； 绒毛膜癌不表达蛋白1； 肺癌相关蛋白Y；
背景信息：
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.
