基因名：
Esrp2
产品别名：
9530027K23Rik； Rbm35b； Esrp2； epithelial splicing regulatory protein 2； epithelial splicing regulatory protein 2； epithelial splicing regulatory protein 2； RNA binding motif protein 35b； RNA-binding motif protein 35B； RNA-binding protein 35B； RNA结合蛋白35B； 上皮粘连调控蛋白ESRP2；
背景信息：
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
