基因名：
LIN28A
产品别名：
CSDD1； LIN-28； LIN28； ZCCHC1； lin-28A； LIN28A； lin-28 homolog A； lin-28 homolog A； protein lin-28 homolog A； RNA-binding protein LIN-28； zinc finger CCHC domain-containing protein 1； zinc finger, CCHC domain containing 1； Lin-28同源物A(LIN28A)； RNA结合蛋白LIN28；
背景信息：
LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II.
