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重组乳腺癌易感基因相关蛋白2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Recombinant PALB2
Recombinant partner and localizer of BRCA2 protein
基因名:

PALB2


产品别名:

FANCN; PNCA3; PALB2; partner and localizer of BRCA2; partner and localizer of BRCA2; partner and localizer of BRCA2; mutant partner and localizer of BRCA2; 乳腺癌易感基因相关蛋白2;


背景信息:
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. Essential partner of BRCA2 that promotes the localization and stability of BRCA2. Also enables its recombinational repair and checkpoint functions of BRCA2. May act by promoting stable association of BRCA2 with nuclear structures, allowing BRCA2 to escape the effects of proteosome-mediated degradation.
 
 
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