基因名:
RNF34
产品别名:
CARP-1; CARP1; RFI; RIF; RIFF; hRFI; RNF34; ring finger protein 34; ring finger protein 34; E3 ubiquitin-protein ligase RNF34; FYVE-RING finger protein MOMO; RING finger protein RIFF; RING-type E3 ubiquitin transferase RNF34; caspase regulator CARP1; caspases-8 and -10-associated RING finger protein 1; human RING finger homologous to inhibitor of apoptosis protein; ring finger protein 34, E3 ubiquitin protein ligase; 环指蛋白34;
背景信息:
Has E3 ubiquitin-protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Protects cells against apoptosis induced by TNF. Binds phosphatidylinositol-5-phosphate and phosphatidylinositol-3-phosphate.