基因名:
COLEC12
产品别名:
CLP1; NSR2; SCARA4; SRCL; COLEC12; collectin subfamily member 12; collectin subfamily member 12; collectin-12; collectin placenta protein 1; collectin sub-family member 12; hCL-P1; nurse cell scavenger receptor 2; scavenger receptor class A, member 4; scavenger receptor with C-type lectin; 凝集胎盘蛋白1;
背景信息:
Colec12 is a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. Colec12 is a scavenger receptor that displays several functions associated with host defense. It promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast and mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells.