基因名:
CABLES2
产品别名:
C20orf150; dJ908M14.2; ik3-2; CABLES2; Cdk5 and Abl enzyme substrate 2; Cdk5 and Abl enzyme substrate 2; CDK5 and ABL1 enzyme substrate 2; interactor with CDK3 2; 细胞周期蛋白依赖性激酶CABLES2;
背景信息:
CABLES2 is a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. ik3-1/CABLES1, a closely related molecule, has been identified to be a candidate tumor suppressor for colon and head/neck cancers. The exact function of this protein is unknown, but it is probably involved in G1-S cell cycle transition. CABLES2 binds to CDK3, CDK5 and ABL1.