基因名:
Pik3ap1
产品别名:
1810044J04Rik; BCAP; Pik3ap1; phosphoinositide-3-kinase adaptor protein 1; phosphoinositide-3-kinase adaptor protein 1; phosphoinositide 3-kinase adapter protein 1; B cell phosphoinositide 3-kinase adaptor; B-cell adapter for phosphoinositide 3-kinase; B-cell phosphoinositide 3-kinase adapter protein 1; 磷酸肌醇-3-激酶衔接蛋白1(PIK3AP1); 磷酸肌醇3激酶接头蛋白1;
背景信息:
B cell adaptor for phosphoinositide 3-kinase (BCAP) is a tyrosine kinase substrate that bridges B cell receptor (BCR) associated kinases to the PIK3 pathway. Syk, Btk or Lyn-dependent tyrosine phosphorylation of BCAP, provides binding sites for the p85 subunit of PIK3. BCAP mRNA is present in mouse spleen, thymus, liver, lung, macrophage and B cell lines. Human BCAP maps to chromosome 10q24.2.