基因名：
SETDB2
产品别名：
C13orf4； CLLD8； CLLL8； KMT1F； SETDB2； SET domain bifurcated histone lysine methyltransferase 2； SET domain bifurcated histone lysine methyltransferase 2； histone-lysine N-methyltransferase SETDB2； SET domain bifurcated 2； chronic lymphocytic leukemia deletion region gene 8 protein； lysine N-methyltransferase 1F； 组蛋白H3-K9甲基转移酶；
背景信息：
Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
