基因名：
KREMEN1
产品别名：
ECTD13； KREMEN； KRM1； KREMEN1； kringle containing transmembrane protein 1； kringle containing transmembrane protein 1； kremen protein 1； dickkopf receptor； kringle domain-containing transmembrane protein 1； kringle-coding gene marking the eye and the nose； kringle-containing protein marking the eye and the nose； KREMEN1蛋白； 含环状结构跨膜蛋白1(KREMEN1)；
背景信息：
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]
