基因名：
RTL6
产品别名：
LDOC1L； Mar6； Mart6； SIRH3； dJ1033E15.2； RTL6； retrotransposon Gag like 6； retrotransposon Gag like 6； retrotransposon Gag-like protein 6； LDOC1 like； Sushi-Ichi retrotransposon homolog 3； leucine zipper down-regulated in cancer 1 like； leucine zipper protein down-regulated in cancer cells-like； mammalian retrotransposon-derived 6； mammalian retrotransposon-derived protein 6； protein LDOC1L； 癌症亮氨酸拉链下调因子1样蛋白；
背景信息：
LDOC1 is a 146 amino acid nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kB (NF-kB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. LDOC1L (Leucine zipper protein down-regulated in cancer cells-like), also known as MART6 (Mammalian retrotransposon-derived protein 6), is a 239 amino acid protein that belongs to the LDOC1 family.
