基因名:
PROK1
产品别名:
EGVEGF; PK1; PRK1; PROK1; prokineticin 1; prokineticin 1; prokineticin-1; EG-VEGF; black mamba toxin-related protein; endocrine-gland-derived vascular endothelial growth factor; mambakine; 内分泌腺来源血管内皮生长因子(EG-VEGF); 内分泌腺衍生血管内皮生长因子; 磷酸化内分泌腺衍生血管内皮生长因子;
背景信息:
The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011]