基因名：
CARD11
产品别名：
BENTA； BIMP3； CARMA1； IMD11； IMD11A； PPBL； CARD11； caspase recruitment domain family member 11； caspase recruitment domain family member 11； caspase recruitment domain-containing protein 11； CARD-containing MAGUK protein 1； bcl10-interacting maguk protein 3； carma 1； 凋亡加强结构域蛋白11；
背景信息：
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
