基因名：
BRSK1
产品别名：
SAD-B； hSAD1； BRSK1； BR serine/threonine kinase 1； BR serine/threonine kinase 1； serine/threonine-protein kinase BRSK1； BR serine/threonine-protein kinase 1； SAD1 homolog； SAD1 kinase； brain-selective kinase 1； brain-specific serine/threonine-protein kinase 1； protein kinase SAD1A； serine/threonine-protein kinase SAD-B； synapses of Amphids Defective homolog 1； 丝氨酸/苏氨酸蛋白激酶SAD-B；
背景信息：
Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.
Tissue specificity: Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.
