基因名:
ZGPAT
产品别名:
GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZIP; ZGPAT; zinc finger CCCH-type and G-patch domain containing; zinc finger CCCH-type and G-patch domain containing; zinc finger CCCH-type with G patch domain-containing protein; g patch domain-containing protein 6; zinc finger CCCH domain-containing protein 9; zinc finger and G patch domain-containing protein; zinc finger, CCCH-type with G patch domain; 锌指蛋白ZGPAT;
背景信息:
ZGPAT is a 531 amino acid protein that contains a G-patch domain, which is typically found within RNA-binding proteins. Proteins that contain the G-patch domain include some tumor suppressor and DNA-damage repair proteins. ZGPAT also contains one C3H1-type zinc finger, which further supports its probable role as an RNA-binding protein. The gene encoding ZGPAT is inactivated via differential methylation in a oligodendroglioma cell line, suggesting that ZGPAT may have utility as a biomarker. There are two isoforms of ZGPAT that are produced as a result of alternative splicing events.